What is the structure of acetaminophen?
C8H9NO2Acetaminophen / Formula
How many polar bonds are in acetaminophen?
Chemical Structure Description The acetaminophen molecule contains a total of 20 bond(s) There are 11 non-H bond(s), 7 multiple bond(s), 1 rotatable bond(s), 1 double bond(s), 6 aromatic bond(s), 1 six-membered ring(s), 1 secondary amide(s) (aliphatic) and 1 aromatic hydroxyl(s).
What is the chemical name of acetaminophen?
N-(4-hydroxyphenyl)acetamide
N-(4-hydroxyphenyl)ethanamide
Acetaminophen/IUPAC ID
Acetaminophen, also known as paracetamol is a medicine used for mild pain relief. It has the chemical formula C8H9NO2, extended formula HOC6H4NHCOCH3, and IUPAC chemical name N-(4-hydroxyphenyl)acetamide.
What kind of bond is acetaminophen?
In these orientations, acetaminophen can form two O:⋯H−O hydrogen-bonds in molecular interaction pairs, and these pairs can be connected by the remaining N−H⋯:N interaction.
How is acetaminophen metabolized?
Acetaminophen is extensively metabolized by the liver via three main hepatic pathways: glucuronidation, sulfation, and CYP450 2E1 oxidation. Approximately 90% of acetaminophen is conjugated to sulfated and glucuronidated metabolites that are renally eliminated.
How is acetaminophen synthesized?
Preparation of acetaminophen involves treating an amine with an acid anhydride to form an amide. In this case, p-aminophenol, the amine, is treated with acetic anhydride to form acetaminophen (p-acetamidophenol), the amide.
Is acetaminophen a polar molecule?
Paracetamol is consistent of the following elements: Hydrogen, Carbon, Nitrogen, and Oxygen (C8H9NO2) Paracetamol is a Polar Molecule because it has no lines of symmetry and not all of the arrows cross out. The Lewis structure has one double bond between C and O. Shape of the molecule is cyclic.
Is Tylenol an NSAID?
Acetaminophen (Tylenol) is known as a non-aspirin pain reliever. It is NOT an NSAID, which is described below. Acetaminophen relieves fever and headaches, and other common aches and pains. It does not relieve inflammation.
Is acetaminophen ionic or covalent?
covalent compound
1. Acetaminophen, C8H9NO2, is a covalent compound and the active ingredient in several popular nonprescription pain medications, such as Tylenol.
What are the metabolites of acetaminophen?
Is acetaminophen metabolized in the kidneys?
Abstract. Acetaminophen (APAP) is normally metabolized in the liver and kidney by P450 enzymes. No toxicity is observed with therapeutic doses of APAP.
What type of reaction produces acetaminophen?
Reactions of Paracetamol (acetaminophen) Hydrolysis (reaction with water) of amides in acidic solution produces an amine and a carboxylic acid.
What is the nature of the bonds in acetaminophen?
Nature of the Bonds. There are 8 different bonds throughout Acetaminophen. This is a double bond between carbon and carbon. It appears 3 times throughout the molecule. The bond is absolutely covalent bond. 2. This is a single bond between carbon and carbon.
What type of bond is acetaminophen ax2?
· Oxygen to Carbon is a moderately polar covalent bond. · Carbon to Nitrogen is a strongly polar covalent bond. · Carbon to Carbon is an absolute, complete covalent bond. The AX form of Acetaminophen is AX2, which means that the Acetaminophen is linear.
Which intermolecular force is the weakest in acetaminophen?
London dispersion is the weakest intermolecular force, and it is regarding an induced dipole. Basically, the electron cloud of this molecule can be distorted by coming into close range with another acetaminophen molecule, which shifts around the partial charges and creates a weak temporary dipole.
What is the volume of distribution of acetaminophen in the body?
Volume of distribution is about 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Acetaminophen appears to be widely distributed throughout most body tissues except in fat.