What antibiotics treat Stenotrophomonas maltophilia?
S maltophilia is consistently susceptible to trimethoprim-sulfamethoxazole (TMP-SMZ) and is a drug of choice. If TMP-SMZ cannot be used, the organism is usually sensitive to doxycycline, minocycline, respiratory quinolones,or ceftazidime. Tigecycline may potentially be helpful, but clinical investigation is needed.
What antibiotics treat Stenotrophomonas?
Trimethoprim-Sulfamethoxazole (TMP-SMX) The mainstay of treatment for Stenotrophomonas infections is trimethoprim-sulfamethoxazole (TMP-SMX) and it remains the current drug of choice.
Does levofloxacin treat Stenotrophomonas maltophilia?
Background: Levofloxacin has been considered as an alternative treatment for Stenotrophomonas maltophilia infection. However, levofloxacin-resistant S. maltophilia (LRSM) are emerging worldwide.
Does ceftriaxone cover Stenotrophomonas maltophilia?
maltophilia infections is not possible, there may be other effective alternative treatments that can be used, namely ciprofloxacin as monotherapy or in combination with other antibiotics, or ceftazidime/ceftriaxone and ticarcillin/clavulanate alone or in combination with other agents.
Does doxycycline cover Stenotrophomonas?
Tetracyclines such as tigecycline, minocycline, and doxycycline are also effective agents and consistently display good activity against S.
Why is Stenotrophomonas resistant to antibiotics?
Abstract. Introduction: Stenotrophomonas maltophilia is a prototype of bacteria intrinsically resistant to antibiotics. The reduced susceptibility of this microorganism to antimicrobials mainly relies on the presence in its chromosome of genes encoding efflux pumps and antibiotic inactivating enzymes.
How do you get rid of Stenotrophomonas maltophilia?
The treatment of choice for Stenotrophomonas maltophilia is trimethoprim-sulfamethoxazole (SXT). Fluoroquinolones (FQs) have in vitro activity against S.
What kills Stenotrophomonas maltophilia?
Can levofloxacin be a useful alternative to trimethoprim sulfamethoxazole for treating Stenotrophomonas maltophilia bacteremia?
Adverse events related to antibiotics occurred more frequently in patients receiving TMP-SMX, and recurrent bacteremia due to levofloxacin-resistant S. maltophilia strains developed in patients treated with levofloxacin. Our data suggest that levofloxacin can be a useful alternative option for treating S.
Does meropenem cover Stenotrophomonas maltophilia?
The susceptibility of 20 clinical isolates of Stenotrophomonas maltophilia to the carbapenems imipenem and meropenem was investigated by various methods. S. maltophilia appeared sensitive to meropenem but resistant to imipenem by disc testing in Iso-sensitest agar.
Does minocycline cover Stenotrophomonas?
Stenotrophomonas maltophilia was the most commonly treated pathogen in our study; minocycline IV therapy resulted in a clinical response rate of 79% and a microbiologic response rate of 72%.
How do you get rid of Stenotrophomonas?
What is Stenotrophomonas maltophiliacultures?
Stenotrophomonas maltophilia: An Emerging global opportunistic pathogen. Clin Microbiol Rev. 2012;25:2–41. [PMC free article][PubMed] [Google Scholar] 2. Kwa AL, Low JG, Lim TP, Leow PC, Kurup A, Tam VH. Independent predictors for mortality in patients with positive Stenotrophomonas maltophiliacultures.
Are nebulizers a source of Stenotrophomonas maltophilia infection?
There is circumstantial evidence that nebulizer equipment may be a source of Stenotrophomonas maltophilia for patients with cystic fibrosis. Eighty-nine inpatient nebulizers were examined for evidence of S. maltophilia contamination of which nine (10%) yielded 14 strains of the bacterium.
Are there alternative treatments for Staphylococcus maltophilia infections?
As an alternative to the use of antibiotics, essential oils from plants like cinnamon, thyme and clove demonstrated the highest level of antimicrobial activity and inhibited all tested strains of S. maltophilia. The use of phage therapy may be an alternative to the use of antibiotics to treat S. maltophilia infections.
Are fluoroquinolones effective for the treatment of Staphylococcus maltophilia infection?
4,7 Fluoroquinolones are an attractive alternative for treating S. maltophilia infection, as they are welltolerated, effective, and have low rates of microbial resistance. 7 Although carbapenems are considered the last resort for treatment of critically ill patients, many mechanisms of resistance have evolved.