What is Osteofibrous dysplasia?
Osteofibrous dysplasia is a noncancerous tumor that typically develops during childhood. It does not spread to other parts of the body and many cases are treated conservatively with careful observation over time. An adamantinoma is a cancerous tumor that is capable of spreading and requires surgery to remove.
How is fibrous dysplasia detected?
The primary tool for diagnosis of fibrous dysplasia is an X-ray. While bone appears solid in an X-ray, a fibrous dysplasia lesion has a relative distinct appearance often described as “ground glass.” The condition may be diagnosed, therefore, even in a person with no symptoms who is getting an X-ray for other reasons.
Does fibrous dysplasia enhance on MRI?
MRI is not particularly useful in differentiating fibrous dysplasia from other entities as there is marked variability in the appearance of the bone lesions, and they can often resemble a tumor or more aggressive lesions.
Is Osteofibrous dysplasia genetic?
Although fibrous dysplasia is a genetic disorder, it’s caused by a gene mutation that’s not passed from parent to child. There’s no cure for the disorder. Treatment, which may include surgery, focuses on relieving pain and repairing or stabilizing bones.
Is adamantinoma serious?
Adamantinoma can also occur in the jaw bone (mandible) or, sometimes, the forearm, hands, or feet. An adamantinoma lump can be painful, swollen and red, and can cause movement problems. Adamantinoma is a serious condition. Treatment is important for survival but it is possible to make a full recovery.
Is fibrous dysplasia treatable?
Is fibrous dysplasia serious?
Fibrous dysplasia is a benign (noncancerous) bone condition in which abnormal fibrous tissue develops in place of normal bone. As these areas of fibrous tissue grow and expand over time, they can weaken the bone — causing it to fracture or become deformed.
Is fibrous dysplasia aggressive?
Although fibrous dysplasia (FD) is a benign fibro-osseous lesion, locally aggressive behaviour has rarely been described but is poorly characterised.
Is fibrous dysplasia progressive?
Fibrous dysplasia is a chronic disorder and is often progressive. Although the lesions may stabilize and stop growing, they do not disappear. Individual lesions may progress more rapidly in the polyostotic form of the condition and in growing children.
What are the imaging features of Osteofibrous dysplasia?
Conclusion: Osteofibrous dysplasia exhibited diverse imaging features ranging from lesions confined to the cortex to more aggressive lesions with complete intramedullary involvement or perilesional marrow edema. Keywords: Bone neoplasms; Magnetic resonance imaging; Osteofibrous dysplasia.
What is Osteofibrous dysplasia of the tibia?
Osteofibrous dysplasia is a benign fibro-osseous cortical lesion that occurs almost exclusively in the tibia and fibula. It is most commonly seen in the mid-diaphysis of the tibia.
What is Osteofibrous dysplasia-like adamantinoma?
Adamantinoma with scarce epithelioid component and mostly composed of osteofibrous dysplasia-like tissue are considered as osteofibrous dysplasia-like adamantinoma. Osteofibrous dysplasia is classically a lytic lesion centered in the tibial cortex, often with sclerotic margins.
What is the difference between Osteofibrous dysplasia and ossifying fibroma?
Osteofibrous dysplasia and ossifying fibroma of the jaw have similar histological characteristics, but osteofibrous dysplasia shows cytokeratin-positive cells, whereas ossifying fibroma of the jaw shows psammomatous calcification, which are exclusive features.