How does vanadium affect the human body?
At higher doses, vanadium often causes unwanted side effects including stomach discomfort, diarrhea, nausea, and gas. It can also cause a greenish tongue, loss of energy, problems with the nervous system, and kidney damage.
What role does vanadium play?
Vanadium compounds that enter the blood stream are subjected to speciation. The predominant vanadium species in blood are vanadate and vanadyl bound to transferrin. From the blood stream, vanadium becomes distributed to the body tissues and bones. Bones act as storage pool for vanadate.
What is vanadium Nicotinate?
Vanadium nicotinate, a blend of vanadium and niacin (vitamin B3), is generally considered to be one of the most efficient and safest delivery forms of the mineral. Niacin also allows for the release of the vanadium as a biologically active agent.
How is vanadium absorbed in the body?
Vanadium absorbed via the gastrointestinal tract, lungs or parenteral routes is transported in the blood primarily as vanadyl (as vanadate is reduced by glutathione in erythrocytes) bound mostly to transferrin and albumin (Ścibior et al., 2020a,b).
How poisonous is vanadium?
Vanadium pentoxide and sodium metavanadate have a toxicity rating of 5, equivalent to a probable lethal oral dose in humans of 5-50 mg/kg (Gosselin et al., 1984). The elemental metallic form is considered to be non-toxic.
What are the benefits of vanadyl sulfate?
Vanadyl sulfate is a mineral used to treat insulin resistance, prediabetes, and diabetes. Evidence shows vanadyl sulfate works similar to insulin in lowering blood sugar levels. Vanadyl sulfate also improves the performance of insulin within the body.
What is Nicotinate glycinate chelate?
A blend of chromium, glycine, and niacin (vitamin B3), this chelate is a safe and efficient delivery form of the mineral. Niacin also allows for the release of the chromium as a biologically active agent.
Does vanadyl sulfate lower blood sugar?
Where is vanadium found in the human body?
Vanadium is found in all body tissues. Byrne and Kosta (1978) reported concentrations of 3.3, 7.5, and 0.5 ng/g fresh weight in the kidney, liver, and muscle, respectively. Vanadium has also been found in placenta at a concentration of 3 ng/g fresh weight (Thürauf et al., 1978).
How much vanadium is toxic?
Is vanadium a carcinogen?
The International Agency for Research on Cancer (IARC) has classified vanadium pentoxide as possibly carcinogenic to humans based on evidence of lung cancer in exposed mice. The Department of Health and Human Services (DHHS) and EPA have not classified vanadium as to its human carcinogenicity.